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Comparison of the outcome and treatment of psychosis in people of Caribbean origin living in the UK and British Whites - Report from the UK700 trial

机译:英国和英国白人居住在加勒比海地区的人的精神病转归和治疗方法比较-UK700试验报告

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摘要

Background The comparative outcome of psychosis in British Whites and UK African-Caribbeans is unclear. Some report that African - Caribbeans have worse outcome, whereas others claim better symptomatic outcome and a more benign course. Aims To a compare the course, outcome and treatment of psychosis in African Caribbeans and British Whites in a large multi-centre sample. Method A secondary analysis of 708 patients with research diagnostic criteria defined psychosis from a 2-year, randomised controlled trial of case management. Outcome measures (hospitalisation, illness course, self-harm. social disability and treatment received) were adjusted for socio-economic and clinical differences between groups at baseline using regression analysis. Results African-Caribbeans were less likely to have a continuous illness and to receive treatment with antidepressants or psychotherapy. Conclusions The outcome of psychosis is complex but differs between UK African-Caribbeans and British Whites. This may reflect risk factors that increase the rate of psychosis in UK African Caribbeans. Treatment differences require further investigation.
机译:背景尚不清楚英国白人和英国非洲加勒比地区精神病的相对结果。一些报告说,非洲-加勒比海地区的结局较差,而另一些人则称其为症状较好的结局和较温和的病程。目的在一个大型的多中心样本中,比较非洲加勒比海地区和英国白人的精神病病程,结果和治疗。方法通过一项为期2年的病例管理随机对照试验,对708名具有研究诊断标准的患者进行了二次分析,确定了精神病。在基线时使用回归分析对两组之间的社会经济和临床差异进行调整,以评估结果指标(住院,病程,自残,社会残疾和接受的治疗)。结果非洲-加勒比地区连续性疾病和接受抗抑郁药或心理治疗的可能性较小。结论精神病的结局很复杂,但英国的非洲加勒比海地区和英国的白人之间差异很大。这可能反映了风险因素,这些风险因素增加了英国非洲加勒比海地区的精神病发病率。治疗差异需要进一步调查。

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